diff --git a/src/sfizz/FilePool.cpp b/src/sfizz/FilePool.cpp
index 8b4ca8a3..9750da2c 100644
--- a/src/sfizz/FilePool.cpp
+++ b/src/sfizz/FilePool.cpp
@@ -216,14 +216,15 @@ absl::optional<sfz::FileInformation> sfz::FilePool::getFileInformation(const Fil
     returnedValue.numChannels = reader->channels();
 
     SF_INSTRUMENT instrumentInfo {};
+    bool haveInstrumentInfo = reader->getInstrument(&instrumentInfo);
 
     FileMetadataReader mdReader;
     bool mdReaderOpened = mdReader.open(file);
 
-    if (!reader->getInstrument(&instrumentInfo)) {
+    if (!haveInstrumentInfo) {
         // if no instrument, then try extracting from embedded RIFF chunks (flac)
         if (mdReaderOpened)
-            mdReader.extractRiffInstrument(instrumentInfo);
+            haveInstrumentInfo = mdReader.extractRiffInstrument(instrumentInfo);
     }
 
     if (mdReaderOpened) {
@@ -233,7 +234,7 @@ absl::optional<sfz::FileInformation> sfz::FilePool::getFileInformation(const Fil
     }
 
     if (!fileId.isReverse()) {
-        if (instrumentInfo.loop_count > 0) {
+        if (haveInstrumentInfo && instrumentInfo.loop_count > 0) {
             returnedValue.hasLoop = true;
             returnedValue.loopBegin = instrumentInfo.loops[0].start;
             returnedValue.loopEnd = min(returnedValue.end, instrumentInfo.loops[0].end - 1);
@@ -243,6 +244,9 @@ absl::optional<sfz::FileInformation> sfz::FilePool::getFileInformation(const Fil
         //   prehaps it can make use of SF_LOOP_BACKWARD?
     }
 
+    if (haveInstrumentInfo)
+        returnedValue.rootKey = clamp<int8_t>(instrumentInfo.basenote, 0, 127);
+
     return returnedValue;
 }
 
diff --git a/src/sfizz/FilePool.h b/src/sfizz/FilePool.h
index dcef362c..f05712fd 100644
--- a/src/sfizz/FilePool.h
+++ b/src/sfizz/FilePool.h
@@ -56,6 +56,7 @@ struct FileInformation {
     bool hasLoop { false };
     double sampleRate { config::defaultSampleRate };
     int numChannels { 0 };
+    int rootKey { 0 };
     absl::optional<WavetableInfo> wavetable;
 };
 
diff --git a/src/sfizz/Region.cpp b/src/sfizz/Region.cpp
index 7ec6619d..83417fb5 100644
--- a/src/sfizz/Region.cpp
+++ b/src/sfizz/Region.cpp
@@ -779,7 +779,12 @@ bool sfz::Region::parseOpcode(const Opcode& rawOpcode)
 
     // Performance parameters: pitch
     case hash("pitch_keycenter"):
-        setValueFromOpcode(opcode, pitchKeycenter, Default::keyRange);
+        if (opcode.value == "sample")
+            pitchKeycenterFromSample = true;
+        else {
+            pitchKeycenterFromSample = false;
+            setValueFromOpcode(opcode, pitchKeycenter, Default::keyRange);
+        }
         break;
     case hash("pitch_keytrack"):
         setValueFromOpcode(opcode, pitchKeytrack, Default::pitchKeytrackRange);
diff --git a/src/sfizz/Region.h b/src/sfizz/Region.h
index 1d402bbe..61d97b27 100644
--- a/src/sfizz/Region.h
+++ b/src/sfizz/Region.h
@@ -382,6 +382,7 @@ struct Region {
 
     // Performance parameters: pitch
     uint8_t pitchKeycenter { Default::pitchKeycenter }; // pitch_keycenter
+    bool pitchKeycenterFromSample { false };
     int pitchKeytrack { Default::pitchKeytrack }; // pitch_keytrack
     int pitchRandom { Default::pitchRandom }; // pitch_random
     int pitchVeltrack { Default::pitchVeltrack }; // pitch_veltrack
diff --git a/src/sfizz/Synth.cpp b/src/sfizz/Synth.cpp
index e63803c1..4dd86f5e 100644
--- a/src/sfizz/Synth.cpp
+++ b/src/sfizz/Synth.cpp
@@ -536,6 +536,9 @@ void sfz::Synth::finalizeSfzLoad()
             if (fileInformation->numChannels == 2)
                 region->hasStereoSample = true;
 
+            if (region->pitchKeycenterFromSample)
+                region->pitchKeycenter = fileInformation->rootKey;
+
             // TODO: adjust with LFO targets
             const auto maxOffset = [region]() {
                 uint64_t sumOffsetCC = region->offset + region->offsetRandom;
diff --git a/tests/FilesT.cpp b/tests/FilesT.cpp
index d0d0b064..dbff1ba1 100644
--- a/tests/FilesT.cpp
+++ b/tests/FilesT.cpp
@@ -684,3 +684,25 @@ TEST_CASE("[Files] Duplicate labels")
     REQUIRE(xmlMidnam.find("<Note Number=\"60\" Name=\"Quux\" />") != xmlMidnam.npos);
     REQUIRE(xmlMidnam.find("<Control Type=\"7bit\" Number=\"20\" Name=\"Bar\" />") != xmlMidnam.npos);
 }
+
+TEST_CASE("[Files] Key center from audio file")
+{
+    sfz::Synth synth;
+    synth.loadSfzString(fs::current_path() / "tests/TestFiles/sample_keycenter.sfz", R"(
+        <group> pitch_keycenter=sample oscillator=off
+        <region> sample=root_key_38.wav
+        <region> sample=root_key_62.wav
+        <region> sample=root_key_38.flac
+        <region> sample=root_key_62.flac
+        <region> pitch_keycenter=10 sample=root_key_62.flac
+        <region> key=10 sample=root_key_62.flac
+    )");
+
+    REQUIRE(synth.getNumRegions() == 6);
+    REQUIRE(synth.getRegionView(0)->pitchKeycenter == 38);
+    REQUIRE(synth.getRegionView(1)->pitchKeycenter == 62);
+    REQUIRE(synth.getRegionView(2)->pitchKeycenter == 38);
+    REQUIRE(synth.getRegionView(3)->pitchKeycenter == 62);
+    REQUIRE(synth.getRegionView(4)->pitchKeycenter == 10);
+    REQUIRE(synth.getRegionView(5)->pitchKeycenter == 62);
+}
diff --git a/tests/TestFiles/root_key_38.flac b/tests/TestFiles/root_key_38.flac
new file mode 100644
index 00000000..d8eefb36
Binary files /dev/null and b/tests/TestFiles/root_key_38.flac differ
diff --git a/tests/TestFiles/root_key_38.wav b/tests/TestFiles/root_key_38.wav
new file mode 100644
index 00000000..e7a27089
Binary files /dev/null and b/tests/TestFiles/root_key_38.wav differ
diff --git a/tests/TestFiles/root_key_62.flac b/tests/TestFiles/root_key_62.flac
new file mode 100644
index 00000000..10006b58
Binary files /dev/null and b/tests/TestFiles/root_key_62.flac differ
diff --git a/tests/TestFiles/root_key_62.wav b/tests/TestFiles/root_key_62.wav
new file mode 100644
index 00000000..658d5bd4
Binary files /dev/null and b/tests/TestFiles/root_key_62.wav differ